Spot the diagnosis 197 - 202

(197) A female of fifty has come with a goitre with well defined margin and India rubber consistency. Her liver and spleen is enlarged . Spot the diagnosis?

(198) A lady of sixty has come with a hard ,irregular and fixed thyroid gland with fracture of neck of femur . Spot the diagnosis?

(199) A lady has come with long standing goitre and has no other complain or finding. Spot the diagnosis?

(200) An old man of seventy has come for a swelling on the femur. On  blood examination his acid phosphatase was found to be raised . Spot the diagnosis?

(201) A patient has come with foot drop . On examination there is tumor of the head of fibula . Spot the diagnosis?

(202) A patient has come with the following features
(a)Pseudoptosis.
(b) Enophthalmous .
(c) Myosis.
(d) Anhydrosis of the affected side of the face .
(a) What is this syndrome known as?
(b) What  is the reason ?

Answers.
(197) Hashimoto's disease.
(198) Carcinoma thyroid.
(199)Secondary toxic goitre.
(200) Prostatic metastasis in bone .
(201) Foot drop is due to involvement of external popliteal nerve by the tumor .
(202a) Horner's syndrome.
(b) Due to involvement of sympathetic trunk .